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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e28be97cd8e7dfc5745ab27d158ec2d318139b4f9f42bc8db0a39c56e9b27f5' 
  AND token = 'mbR7HDP0bQEFaAQ1sL4eDeI25+zly9BdqZ4P+GILxTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}