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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3be7fbc7e5ff37f10352a70a614aa70d7dbdca8378811c29b3a521d57f0121e4' 
  AND token = 'yKz05GQbMlHvUtI0Z186BENRqu74A0N9UT5bvxvCeOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}