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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46200a103dc193bc2b5bfb70b82b0cd8b0fbb503054cd653f462bcac09a97563' 
  AND token = 'OyrPfbKMQAp+2TX65jFBT4+FcSSJWITWJP1SroScg5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}