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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4029c78f7105dc35beb0b1a9a14ee662cbea26453c8e70662b47f1465ff66e12' 
  AND token = 'cumWO1pkzdChrkc+lrUpmTuIXxQD7R+h1WflZ85MWak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}