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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bf411dd47002136651d62a87deb2108ed4825153c79817a60c08de5e72c7731' 
  AND token = 'BW6f8URdaZH6a45QGUtMF6MpepM3bL3wFQMibGXzzIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}