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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8720f6e9ff40d3cfebc927fb48a0118411b8b19f4ce3f964ac0f093528c1062d' 
  AND token = 'SEeOeYAFiGoErUAW01b7FjJAAmXgfLAjPK0qEzEtlRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}