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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '869c289a13f28b2d7e3119c2d31058eeff4f05ea521e74de3bf16b6ec378ca95' 
  AND token = 'nfd0+jJ2DyCQIbec/w7Zi0HAaajH+J3X5DqpFLmtGJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}