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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfe781560ca9e660c2407825f566d7a46dc9b5895162777ba9fc53715a99577f' 
  AND token = 'Zkh9Hu+k/PlbLzR6rTS0UDyRV4e0WIsS0EWmLaagxBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}