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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c11729e52731f6d802c9d4d41e1e7dc5487c2bc2289ace51e68110d4972c432e' 
  AND token = 'rTPtJUGQxoMcYUUYGALKaFJnnY6kIEy0N/FHYFFCQtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}