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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55d3772861b3d46efb23f60a65f037cb972200a2425652e26e0b7d47599fb16f' 
  AND token = 'TPsZ6V+50wRWGrAlmLQ1AZtUeSCIoRlNSCXKhnaky4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}