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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e670606f839f99e4331e31e3d8011b42de9a369a5ee31f48ac2be393903e516' 
  AND token = '0IiVZcFZiNXC03i3DIdyb3JIiDOg0ufRGjqPREETbtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}