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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e95142591c3484d9c5836977426ca7ecd015093ae97515c51199714e110f8485' 
  AND token = 'MlNcguYY9Qaqe+mswgwjIR31Wge1K0XrofvGfTWP18o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}