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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f724eb7fb9259e869cf76ecf1f253e7a236fd86c2b42362bfbd6757a15be9a' 
  AND token = 'iRafr8uZf2DeeLNLH3KwVF71BnngbQTfJWSUZR2c9dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}