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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d00a85efe1c126aa782a9a80dc70d49a6bf070eed53b29ff9dd863505cf8cb' 
  AND token = 'F2DVYF8VNyXKxOCiQJfgQgdhqjoxdZUwqSb2nNT2evw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}