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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1158e80eb2ac67fd17ec2254961b37febad6b4b09d9e74d75f9850e3b9198e7e' 
  AND token = 'r0Zk3UyRP1r4LRE2eDdFxZzD9bHP8UDpDzLVMvoVXoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}