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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '734f8b95d93b273a9e8c0167edafb0bd5d8e33ab67be27ab0949d3822c37c721' 
  AND token = 'hcb/SrnZxYjyxnM5iCMFpsZ57FgqxPZyOLjXzd1o/6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}