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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee0454c8119e4bbf5096880cf74d5c6c52f29da39d86daa2596e14c3c9038b3a' 
  AND token = 'XbiEcizRLByOKbVT4nfWwVTt7rRFfLFHsHlTRTbVv9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}