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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dab2ef79711bed1226ad8ab9cfd1a604895a083a86185ab2b73bcd0f8363194' 
  AND token = 'RuWzGLQgv7kcSnncDgXO0RGa2G0vYqOkux99JacXfnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}