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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ce616817a8f91e35fa2d1cedbc49975471ee193cc08b3b3b01489aae7b25a5' 
  AND token = 'Q4fr9R6KuOHnN49QynbTnJh6/Gbhkrjn+aH0HL8kziY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}