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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5061e6f189ec4aed4d5fe2585ec75c541bd3e1402aeeff54b8c230744dbfbad' 
  AND token = 'yQyf+ki6zgkJTDF0CnwZZNBh7N2MqcUea9JBVxnV6GQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}