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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8df673b5d9d9f41089fc71776fc4aefd5b34ea5e37863181c38ff4bbf15b239' 
  AND token = 'OImcR2mJQ5EZQnOFiXnNVA4ro2uGS7JpRkTS9qww7dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}