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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb9aac0b85970c8788eb6e4bee1cc8e00b9bb481d8cee88388b7484137637eed' 
  AND token = 'hq7jC014hbPlCR92F7pu4hvPwmdJ4pwuLHicRN7/qQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}