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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4f7ec2255e3a81c23d5492a0bdeb24d13cb39e809ade2e3b20e59215041ec8b' 
  AND token = '6u0x8n6hBU0t4SroAdiB8Davaw0mfGbKlPGbAVLvM58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}