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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '693a6d2f740d7ba99c39d7f372bc1c6d3d4c1007b4579b64c488f8a828d90698' 
  AND token = 'u5ICIHcdxDhG3vaFVH0lmjl8LYoyvmZdApEtHnRgEZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}