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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd280e70cca4f472af707aaa6550e9d7858b21e7f0008c3eff24386edf3d137bc' 
  AND token = 'jABBa2hiNMhrMKTRJy1AV/HmxjC9WacaqXeAW1YhL1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}