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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70a0783206437677b07ac8582c2a734b15408be4e46a13d13f8bc740b55ed24c' 
  AND token = 'I2iBUO5sE4As3UBwuPkqIGf05XQXEVB7/pf5EuNgLWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}