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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f1218ca2e2e2cd734b58d682446e6d85f6f865bd704d2800e25b4cbc7493e36' 
  AND token = 'AU5lLK3reMPSfcPGISb3j7Y6Usg0MimzMGCkx2P/Z58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}