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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dba66f0f37db88407a11c6f97c30a98406cf957d820ad80b50f5a46696c256e' 
  AND token = 'EDk7+d3OljZEdqT+Hqp21nrblz9PgY/X9GHmocAuecI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}