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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb0a7fed0f175455d76335d7ea653d5bf64e0ebe0e3ffff96e3af7cca63fb597' 
  AND token = '6zV1gKq5JdzaNbT0yy2yRNTvH/XiWbNhYwR36bvjTWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}