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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5457e4fa287103fe646d2e89197d06e9ce998895278f62ebc5b6b756b5b98ce5' 
  AND token = '+ehPtMpYXaPQoyHhDyfF9OMoUwYOG1W7W82hYvuxNeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}