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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049b32f8871db1e65739613925fc0335e9b5b2d2fb1de39c921a937553092b9e' 
  AND token = '4WuPe0/WHf2Qz9d0CUqEmSnsblgAIz1TS9QKbrq9S/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}