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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15dffd84f4b5c80b53a11474aadd33cbd5da9035e2a3cf5b1894767c14410486' 
  AND token = 'NVWXsz0kq/KTbted7PEL13CjF/J/KwA3KV6pbE1nTQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}