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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3e618cc88bb0e3f1f0016aafa1f416ac3ce2ea9de72deb33148f18a73871925' 
  AND token = 'wJMm1F9GT0XO8UFVCllrpdfHkVPLTow3V4gwAVqTIxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}