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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c188ad518fdebd086c9556d43886dc29cd34046b080bb6f63b2f2d4e2c2c7705' 
  AND token = 'G+NYfU9nrqMNSVPU9/YLwp58XYF8lejgolg0sopOedU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}