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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f593569758ed3f1e770867db3e857487647445f63af8b8c7a91c80cc41e9749' 
  AND token = 'JNVuMjCCRAT4dtX2oQJQvCB2Sby44KTkhdGcaFuKAlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}