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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec7a2641078625f73139df37bcc20349ed91e199fab9159719e06e6099a507d' 
  AND token = 'H19q7J2wac196Lzxu0+eGewtNQGe473xlt16xqctM00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}