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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff7e22148caf179fd568f291afcd16fb1d46d3a6779d9477c3ba07d24b8a9c8' 
  AND token = 'l7Aer4Q3uFxUoY5pQE+536iE07oW2BRxPJap0Tz88qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}