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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fcefb4922057c8ddc75661326f3e8bebcf62cd42abd351c4c292fe6fe4c3447' 
  AND token = '8gSPb7R/E6pvVMHBsQt4subust9MumtUhwtSWBBdSw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}