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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4677c8c1dd167324418f8239076cb7e4820ff22e6456d665a21af16f4dbe71b9' 
  AND token = 'Rd+Gq0dY1CJtHqmtf9RkRZmddgAVBXl//686uFPxdJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}