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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a59f0ac2044d0332dc56f6841697a9e5aa94549659014bfd62c42614dd8ad5c5' 
  AND token = '4/P+7M1PsmewmpBaeH5Et8IHlxUEdMdXWey2PagMOsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}