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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ea61d8b6ce77f0492f17f01ad9463ee82b198861f0081fc2b4bbf3ea4f9d931' 
  AND token = 'P+Dr1DnVaOb16H6DnUiQlvnaH8LHOeRv5PPdAMgXMxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}