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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d5aea19be61d511fa347b20fe8403fc0da8330b8e49ed94281216b16c7cdf53' 
  AND token = 'cEa0NNciqAtlhT/8s5gD3bLqHPheldqKkIbANWlSGrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}