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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6125620da6509fb13223b92ae15b226aa7a2708fe1e0431f4bff906fa9274336' 
  AND token = 'RGSI+I9H+3aH5kC4VOQdiKSwMcGCTvUUCnBcuRRDcjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}