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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ab5d3bcf65a127b58bf8e628309d0309cbd7e410cc6df9026d22e5f92043beb' 
  AND token = 'wq1E2j4q2L1wXde2Fb0dy/PZkxGcFGszhMviNjh0vYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}