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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3299df5fcbfa53ff66fb144fc8794f2da20f4aad885a5992e998f38fab561534' 
  AND token = '5UMDPedwMJ2uztVhL4g5KBPncpBkLVxNazr4fBFd8lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}