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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c25694dd9b0f0b132dda5b1691a5a9249695a76e64f3dd924c0e95bebbeed35b' 
  AND token = 'UySewP+1s2XFU69dDUK11BEQWq91TytCOi0fsDIL3eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}