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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '361e99e9f779aff8bc036d58b1d646427ddf78ca87ad77c5c0895ea7c3c4090b' 
  AND token = 'cB3JTeK+1V7QpLJoXooWSvI/eY+L7eteMgtkAFJCrSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}