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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cc66ef161dd5d0f7f770476c636cfc7f685970be67cdb9413168c03e1c7ce05' 
  AND token = '7mGigC4SFMQgVDUmq/zBVVXwec2lW0Wg70zG5WAz2Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}