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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e37aa9ef1871751a312e91b911d6b9afd5706737d048cd1e24246d9167c67325' 
  AND token = 'z8Lg7XWylHg1U3vjENf8v1BuLmRicIh8ccdYC2BE+4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}