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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd64b3035b2d6d014a550ace779ce1bb30a1db01f71047c6798a25d4a3ff977df' 
  AND token = 'gSomdQId72t/fWQmzEVY90AJxzHDI2J+IPzC31XSBOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}